Trialect

Active

Anemia and Red Blood Cell Clinical Translational Research - On Hold - Do Not Apply

University of Zurich
(5/5) - 1 reviews

University of Zurich

Main Areas of Interest

This is a Trialect partnered Traineeship program that is exclusively available to the registered members of Trialect. This program includes research on patients as well as in the lab;

We are experts in the investigation of red blood cell volume regulation, detection of density, deformability and metabolic state of cells. We are interested in detection of cytoskeletal disorganization and defects associated with facilitated proteolysis in red blood cells. We have experience in working with blood samples of health humans and patients with hereditary rare anemias (sickle cell disease, spherocytosis, xerocytosis, cryohydrocytosis, PK and G6PD deficiencies and further idiopathic hereditary disorders associated with hemolysis and increased red cell turnover or inefficient erythropoiesis. Measuring intraerythrocytic free Ca2+ levels, membrane permeability to Ca2+ and function of Ca2+ pumps as well as following on Ca2+-dependent processes in red cells is our specialty.

We are the leading house for the RELEVANCE project on Regulation of red cell life-span, erythropoiesis, survival, senescence and clearance (http://relevance.arivis.com/) and a partner within the CoMMiTMenT project network on Combined Molecular Microscopy for Therapy and Personalized Medication in Rare Anaemias Treatments

Techniques You Will Learn

We are routinely applying the following experimental techniques:

Na+, K+ intracellular and extracellular concentrations (flame photometry, gravimetry, ion-selective electrodes)
K+ loss, glucose uptake, and lactate production rates in RBC suspension/whole blood (electrodes, enzymatic micro-assays)
Cell density, volume, hydration state: Percoll density gradient, microfluidic test, (intracellular Na+K), morphometry
O2 dissociation curve: HEMOX analyser
Ca2+ movements and intracellular content: fluorescent dye fluo-4 AM (micro-fluorescence imaging – microscopy and flow cytometry)
Filtration assay (deformability, membrane stability)
Cytoskeletal integrity (microscopic test and SDS page)
GSH/GSSG – Ellmann’s reagent, glutathione reductase
ATP: bioluminescent test
NO2-/NO3-: chemiluminiscence test (CLD-88)
We may detect activity of single ion transport systems (Na,K-ATPase, Na,K,2Cl- and K-Cl- cotransporter, Na/H exchanger, Gardos channels, NMDA receptors) using radiolabeled tracer kinetics and radiolabeled antagonist binding assays
To come soon: microfluidic red cell adherence technique

Curriculum

Can Be Customized

Accommodation

We have this place: https://www.accademia.li/

We have some youth hostels, but they are rather far away. The closest hotel would be Coronado, but it is rather expensive http://www.welcomehotels.ch/en/coronado/

Try airbnb.com

Fees and Program Logistics

This program has the following durations available:

Duration	Fee

Who Can Apply

Host Details

Host Name: Anna Yu. Bogdanova

Affiliation: University of Zurich

Address: Winterthurerstrasse 260; CH-8057; Zürich

Website URL: http://www.uzh.ch/en.html

Disclaimer:It is mandatory that all applicants carry workplace liability insurance, e.g., https://www.protrip-world-liability.com (Erasmus students use this package and typically costs around 5 € per month - please check) in addition to health insurance when you join any of the onsite Trialect partnered fellowships.

Legal & Affiliation Disclaimer

Affiliation Disclaimer: Trialect operates independently and is not affiliated with, endorsed by, or supported by any sponsors or organizations posting on the GrantsBoard platform. As an independent aggregator of publicly available funding opportunities, Trialect provides equal access to information for all users without endorsing any specific funding source, content, organization, or sponsor. Trialect assumes no responsibility for the content posted by sponsors or third parties.

Subscription Disclaimer: Upon logging into Trialect, you may choose to SUBSCRIBE to GrantsBoard for timely notifications of funding opportunities and to access exclusive benefits, such as priority alerts, reminders, personalized recommendations, and additional application support. However, users are advised to contact sponsors directly for any questions and are not required to subscribe to engage with funding opportunities.

Content Ownership and Copyright Disclaimer: Trialect respects the intellectual property rights of all organizations and individuals. All content posted on GrantsBoard is provided solely for informational purposes and remains the property of the original owners. Trialect does not claim ownership of, nor does it have any proprietary interest in, content provided by third-party sponsors. Users are encouraged to verify content and ownership directly with the posting sponsor.

Fair Use Disclaimer: The information and content available on GrantsBoard are compiled from publicly accessible sources in alignment with fair use principles under U.S. copyright law. Trialect serves as an aggregator of this content, offering it to users in good faith and with the understanding that it is available for public dissemination. Any organization or individual who believes their intellectual property rights have been violated is encouraged to contact us for prompt resolution.

Third-Party Posting Responsibility Disclaimer: Trialect is a neutral platform that allows third-party sponsors to post funding opportunities for informational purposes only. Sponsors are solely responsible for ensuring that their postings comply with copyright, trademark, and other intellectual property laws. Trialect assumes no liability for any copyright or intellectual property infringements in third-party content and will take appropriate action to address any substantiated claims.

Accuracy and Verification Disclaimer: Trialect makes no warranties regarding the accuracy, completeness, or reliability of the information provided by sponsors. Users are advised to verify the details of any funding opportunity directly with the sponsor before taking action. Trialect cannot be held liable for any discrepancies, omissions, or inaccuracies in third-party postings.

Notice and Takedown Policy: Trialect is committed to upholding copyright law and protecting the rights of intellectual property owners. If you believe that content on GrantsBoard infringes your copyright or intellectual property rights, please contact us with detailed information about the claim. Upon receipt of a valid notice, Trialect will promptly investigate and, where appropriate, remove or disable access to the infringing content.

Onsite/On-Campus Program

Traineeship

United States

Application Review Deadline:

Jan 15th, 2026

Apply Now

Featured Reviews

5

1 reviews

Excellent

Very good

Average

Poor

Terrible

J Francis Borgio 5 years ago

(5/5)

Me and my mentor (Prof Dr. Anna Yu. Bogdanova) have collaborated already and have applied for a funded research project on the area of specialization. It was a great professional opportunity to be a part of the Clinical Translational Research-Anemia and Red Blood Cells Traineeship. Prof Dr. Anna Yu. Bogdanova and her research team were very supportive and great teachers. In my laboratory, we have established the techniques learned during the program. I have learned the most appropriate techniques needed to achieve the objectives of the ongoing research. We are in the path of developing novel protocols for the early prenatal identification of genetic diseases using the techniques learned from the Trialect Traineeship. The program was well designed and executed appropriately. I am okay for the future fellows to contact me.