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Academic-Industrial Partnerships for Translation of Technologies for Diagnosis and Treatment (R01 - Clinical Trial Optional)

National Institutes of Health

The purpose of this Notice of Funding Opportunity (NOFO) Announcement is to stimulate efforts to translate scientific discoveries and engineering developments into methods or tools that address problems in basic research to understand disease, or in applied research to assess risk, detect, prevent, diagnose, treat, and/or manage disease. The rationale is to deliver new capabilities to meet evolving requirements for technologies and methods relevant to the advance of research and delivery of care in pre-clinical, clinical and non-clinical settings, domestic or foreign, for conditions and diseases within the missions of participating institutes.

This NOFO specifies a partnership structure that is expected to help bridge gaps in knowledge and experience by engaging the strengths of academic, industrial, and other investigators. The partners on each application should establish an inter-disciplinary, multi-institutional research team to work in strategic alliance to implement a coherent strategy to develop and translate a solution to their chosen problem. They are expected to plan, design, and validate that the solution will be suitable for end users. Each partnership should include at least one academic and one industrial organization. Each partnership should plan to transition a technology, method, assay, device, and/or system from a demonstration of possibility to a status useful in the chosen setting. Funding may be requested to enhance, adapt, optimize, validate, and otherwise translate technologies that address problems in biology, pathology, risk assessment, diagnosis, treatment, and/or monitoring of disease status.

This NOFO defines "innovation" as likelihood to deliver a new capability to end users.

This NOFO will support clinical trials that test functionality or validate performance in the chosen setting. This NOFO is not intended to support clinical trials that lack translation as the primary motivation. Applications that propose phase III clinical trials iare not sought by and will not be supported through this NOFO. This NOFO does not propose to support commercial production or basic research projects.

Companion FOA: PAR-25-338 , R01 Research Project

Deadlines:

Application Due Date(s): Feb. 5, Jun. 5, Oct. 5

PAR-25-337 Expiration Date January 8, 2028

Specialties

Engineering and Physical Sciences

Medical

Medical - Clinical Science

Interdisciplinary

Medical - Basic Science

Medical - Translational

Eligibility Requirements

Sponsor Details

Sponsor Institute/Organizations: National Institutes of Health

Sponsor Type: Government/Federal

Address: NA

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